New pyrimidine derivatives with side chains of amino acids.

An exceptional series of phase transitions in hydrophobic amino acids with linear side chains

The solid-state phase transitions and intermediate structures of S-2-amino-butanoic acid (l-2-aminobutyric acid), S-2-aminopentanoic acid (l-norvaline), S-2-aminohexanoic acid (l-norleucine) and l-methionine between 100 and 470 K, identified by differential scanning calorimetry, have been characterized in a comprehensive single-crystal X-ray diffraction investigation. Unlike other enantiomeric ...

A practical route to β2,3-amino acids with alkyl side chains

Enantiopure N(Boc)-β(3)-amino nitriles, valuable synthetic intermediates in the multistep homologation of α-amino acids, were alkylated using n-BuLi as base. Alkylations afforded easily separable, almost equimolecular mixtures of diastereomeric N(Boc)-protected syn and anti β(2,3)-amino nitriles. Suitable manipulations of both cyano and amino groups eventually led to enantiopure N- and/or C-pro...

Mutant D amino acid oxidase with higher catalytic efficiency toward D amino acids with bulky side chains*

aA. N. Bach Institute of Biochemistry, Russian Academy of Sciences, 33 2 Leninsky prosp., 117234 Moscow, Russian Federation. Fax: +7 (495) 954 2732. E mail: [email protected] bInnovations and High Technologies MSU Ltd., office 96, 16 ul. Tsimlyanskaya, 109559 Moscow, Russian Federation. Fax: +7 (495) 939 3208 cDepartment of Chemistry, M. V. Lomonosov Moscow State University, 1 Leninskie Gory,...

Transition Metal Complexes of Amino Acid and Peptide Derivatives Containing Carboxylate and Imidazole Side Chains

CHIRAL SEPARATIONS Amino Acids and Derivatives See III /AMINO ACIDS AND DERIVATIVES: CHIRAL SEPARATIONS

use by the OPCW inspectorate. Use of GC with one or more spectrometric technique such as mass spectrometry is required to conRrm the presence of chemical warfare agents. For this reason many analyses are carried out by GC-MS under electron impact or chemical ionization conditions. For analyses involving low levels of chemical warfare agents in the presence of high levels of interfering chemical...